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Symbol
Name
ID

Abcc6
ATP-binding cassette, sub-family C member 6
MGI:1351634

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes

Gastrointestinal hemorrhage

Retinal hemorrhage

Cerebral hemorrhage

Bruising susceptibility

Abnormal retinal artery morphology

Abnormal cardiovascular system morphology

Right atrial enlargement

Myocardial calcification

Ventricular hypertrophy

Abnormal endocardium morphology

Mitral valve prolapse

Dilated cardiomyopathy

Restrictive cardiomyopathy

Pericardial effusion

Cardiomegaly

Aortic dissection

Calcification of the aorta

Abdominal aortic calcification

Coronary artery atherosclerosis

Premature coronary artery atherosclerosis

Coronary artery calcification

Renal artery stenosis

Arterial calcification

Carotid artery calcification

Generalized arterial calcification

Medial calcification of large arteries

Medial calcification of medium-sized arteries

Arterial stenosis

Premature occlusive vascular stenosis

Arteriosclerosis

Atherosclerosis

Accelerated atherosclerosis

Vascular dilatation

Abnormal cerebral vascular morphology

Stroke

Transient ischemic attack

Reduced left ventricular ejection fraction

Left ventricular systolic dysfunction

Mitral regurgitation

Mitral stenosis

Tricuspid regurgitation

Hypertension

Renovascular hypertension

Weak pulse

Intermittent claudication

Pulmonary arterial hypertension

Sinus tachycardia

Sudden cardiac death

Myocardial infarction

Angina pectoris

Congestive heart failure

Cardiogenic shock

Telangiectasia of the skin

Disease(s) Associated with ABCC6

arterial calcification of infancy

coronary artery disease

pseudoxanthoma elasticum

Mouse Phenotypes		calcified artery	abnormal kidney vasculature morphology	decreased susceptibility to dystrophic cardiac calcinosis	increased susceptibility to dystrophic cardiac calcinosis
Availability	Mouse Genotype	calcified artery	abnormal kidney vasculature morphology	decreased susceptibility to dystrophic cardiac calcinosis	increased susceptibility to dystrophic cardiac calcinosis
	Abcc6^{Dyscalc1-C3H/HeNCrl}/Abcc6^{Dyscalc1-C3H/HeNCrl}
	Abcc6^{Dyscalc1-C57BL/6J}/Abcc6^{Dyscalc1-C57BL/6J}
	Abcc6^{Dyscalc1-C57BL/10}/Abcc6^{Dyscalc1-C57BL/10}
	Abcc6^{Dyscalc1-DBA/2J}/Abcc6^{Dyscalc1-DBA/2J}
	Abcc6^rs32756904-T/Abcc6^rs32756904-T
	Abcc6^tm1Aabb/Abcc6^tm1Aabb
	Abcc6^tm1Jfk/Abcc6^tm1Jfk
	Abcc6^{Dyscalc1-C3H/DiSnA}/Abcc6^{Dyscalc1-C57BL/10}
	Abcc6^rs32756904-T/Abcc6^{Dyscalc1-C57BL/6J}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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